Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203318 | 0.80 | PSMB5 (0.38) | METAP2LMNATSHRMAPTHPGD | |
| SCHEMBL2482030 | 0.78 | DHODH (0.37) | METAP2PTGS1PTGS2HTR2CCYP1A2 | |
| SCHEMBL2962655 | 0.78 | AKR1C3 (0.38) | TSHRAKR1C3AKR1C2AKR1C1HPGD | |
| SCHEMBL3159359 | 0.77 | METAP2 (0.40) | METAP2LMNAPTGS1MEN1PTGS2 | |
| SCHEMBL29949127 | 0.75 | ALDH1A1 (0.33) | MAPTESR2 | |
| SCHEMBL14645967 | 0.75 | ALDH1A1 (0.33) | MAPTESR2 | |
| SCHEMBL3964697 | 0.75 | GABRA1 (0.37) | — | |
| SCHEMBL1453124 | 0.73 | — | — | |
| SCHEMBL1827132 | 0.73 | PDCD1 (0.39) | KMT2ATSHRHPGD | |
| SCHEMBL30229874 | 0.73 | PDCD1 (0.39) | KMT2ATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746289-B1 | Catalysts | BOREALIS AG (AT) | 2017-09-27 | — | — | EP | disclosed |
| US-9469699-B2 | Catalysts | BOREALIS AG (AT) | 2016-10-18 | — | — | US | disclosed |
| US-20160002369-A1 | CATALYSTS | BOREALIS AG (AT) | 2016-01-07 | — | — | US | disclosed |
| WO-2014096164-A1 | CATALYSTS | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |
| EP-2746289-A1 | Catalysts | Borealis AG (AT) | 2014-06-25 | — | — | EP | disclosed |
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002369-A1 | CATALYSTS | SIGMAR1, SFN, AP3S1 | METAP2 3048/4885LMNA 2545/4885PTGS1 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.