Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932984 | 0.92 | MAPT (0.43) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28303519 | 0.87 | PLA2G7 (0.46) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11011101 | 0.84 | CA12 (0.43) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27957723 | 0.81 | MAPT (0.50) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7408997 | 0.81 | MAPT (0.46) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2476400 | 0.81 | MRGPRX4 (0.47) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10452462 | 0.81 | CYP11B2 (0.48) | CYP11B1CYP11B2 | |
| SCHEMBL19128162 | 0.80 | TRPV4 (0.48) | MAOBMAOACYP11B1CYP11B2TRPV4 | |
| SCHEMBL5314618 | 0.79 | CYP11B1 (0.45) | MAOBCYP11B1CYP11B2TRPV4PLA2G7 | |
| SCHEMBL7323185 | 0.78 | CYP11B1 (0.65) | MEN1MAPTKMT2AMAOBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-B1 | GLUCOCORTICOID RECEPTOR MODULATORS | KAROBIO AB (SE) | 2009-07-29 | — | — | EP | disclosed |
| US-6583180-B2 | Antidiabetic agents | ABBOTT LABORATORIES | 2003-06-24 | — | — | US | disclosed |
| US-20020156311-A1 | Glucocorticoid receptor modulators | KARO BIO AB (SE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156311-A1 | Glucocorticoid receptor modulators | NR3C1, NR5A1, NR3C2 | MEN1 2380/4885LMNA 4760/4885MAPT 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.