Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.41 |
| ▸ | PPARA | Q07869 | 14/20 | 0.41 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954496 | 0.87 | PPARD (0.50) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3965972 | 0.83 | PPARD (0.59) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2166925 | 0.76 | PPARD (0.50) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2166493 | 0.73 | HSD11B1 (0.43) | PPARDPPARAMEN1ALDH1A1CYP3A4 | |
| SCHEMBL6302340 | 0.72 | PPARD (0.74) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3889190 | 0.71 | TRPA1 (0.36) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL5482065 | 0.71 | PPARD (0.52) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3954490 | 0.71 | PPARD (0.68) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2166533 | 0.70 | TP53 (0.45) | PPARDPPARAMEN1ALDH1A1CYP3A4 | |
| SCHEMBL280301 | 0.68 | TP53 (0.44) | PPARDPPARAPPARGALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501811-B1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-07-15 | — | — | EP | disclosed |
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-08-02 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| EP-1501811-A4 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2006-02-08 | — | — | EP | disclosed |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2005-08-11 | — | — | US | disclosed |
| EP-1501811-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | Kang, Heonjoong (KR) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003106442-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885PPARG 2/4885 |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.