Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.52 |
| ▸ | PPARA | Q07869 | 11/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482061 | 0.84 | PPARD (0.70) | PPARDPPARAPPARGMAPT | |
| SCHEMBL3954496 | 0.82 | PPARD (0.50) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3889190 | 0.76 | TRPA1 (0.36) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3965973 | 0.71 | PPARD (0.41) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2166493 | 0.70 | HSD11B1 (0.43) | PPARDPPARAMEN1ALDH1A1CYP3A4 | |
| SCHEMBL2166533 | 0.68 | TP53 (0.45) | PPARDPPARAMEN1ALDH1A1CYP3A4 | |
| SCHEMBL5483798 | 0.66 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL3954490 | 0.66 | PPARD (0.68) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL280301 | 0.65 | TP53 (0.44) | PPARDPPARAPPARGALDH1A1CYP3A4 | |
| SCHEMBL2468793 | 0.65 | PPARD (0.56) | PPARDPPARAPPARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841748-B1 | ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE | SEOUL NAT UNIV IND FOUNDATION (KR) | 2011-12-28 | — | — | EP | disclosed |
| EP-1841748-A1 | ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE | Kang, Heonjoong (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006071103-A1 | ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE | KANG HEONJOONG (KR) | 2006-07-06 | — | — | WO | disclosed |