Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536041 | 0.85 | ALOX5 (0.32) | ALOX5KDM4CEPHX2TAAR1 | |
| SCHEMBL3966749 | 0.76 | ALOX5 (0.35) | PDE10AALOX5CA1CA2TSHR | |
| SCHEMBL3968067 | 0.76 | CYP3A4 (0.42) | PDE10AALOX5CA1CA2TSHR | |
| SCHEMBL3969449 | 0.75 | ALOX5 (0.41) | PDE10AALOX5CA1CA2TSHR | |
| SCHEMBL8140503 | 0.73 | PDE10A (0.45) | PDE10AALOX5CA1CA2TSHR | |
| SCHEMBL3975247 | 0.72 | TDP1 (0.46) | PDE10AALOX5SMN1; SMN2 | |
| SCHEMBL3977541 | 0.69 | CHRNB4 (0.38) | ALOX5 | |
| SCHEMBL3970430 | 0.69 | PDE10A (0.42) | PDE10AALOX5TSHRCASP1SMN1; SMN2 | |
| SCHEMBL2739345 | 0.69 | PDE10A (0.52) | PDE10AALOX5CA1CA2TSHR | |
| SCHEMBL3965393 | 0.68 | KDM4E (0.43) | ALOX5CA1CA2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359890-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-6673934-B2 | 4-AMINO-2-(1-ARYLOXY-ETHYL)PHENOL COMPOUND | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359890-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-31 | — | — | US | disclosed |
| WO-2002058631-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | AOX1, CYC1, CBR1 | PDE10A 2017/4885ALOX5 276/4885CA1 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.