Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968161 | 0.85 | PDE10A (0.39) | ALOX5EPHX2TAAR1KDM4C | |
| SCHEMBL6535775 | 0.75 | — | — | |
| SCHEMBL6535648 | 0.74 | POLB (0.43) | ALOX5 | |
| SCHEMBL6535756 | 0.74 | TDP1 (0.39) | GAA | |
| SCHEMBL3654298 | 0.71 | CASP1 (0.37) | ALOX5GAA | |
| SCHEMBL6535654 | 0.70 | TDP1 (0.48) | GAA | |
| SCHEMBL6535758 | 0.69 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL827776 | 0.68 | — | — | |
| SCHEMBL22283000 | 0.68 | GAA (0.37) | ALOX5GAA | |
| SCHEMBL6535617 | 0.68 | CHRNB2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359887-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6673932-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359887-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2003-07-17 | — | — | US | disclosed |
| WO-2002058658-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, COX5A | ALOX5 301/4885EPHX2 1121/4885TAAR1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.