Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969449 | 0.90 | ALOX5 (0.41) | CYP3A4KDRMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL3975247 | 0.86 | TDP1 (0.46) | CYP3A4MAPTSMN1; SMN2ALOX5PDE10A | |
| SCHEMBL6535648 | 0.83 | POLB (0.43) | CYP3A4KDRTP53LMNAADORA3 | |
| SCHEMBL3977541 | 0.83 | CHRNB4 (0.38) | LMNAPOLBALOX5MEN1ALDH1A1 | |
| SCHEMBL3968205 | 0.81 | ALOX5 (0.35) | CYP3A4LMNAMAPTALOX5PDE10A | |
| SCHEMBL11510925 | 0.80 | POLB (0.43) | CYP3A4KDRTP53LMNAADORA3 | |
| SCHEMBL1840074 | 0.79 | GABRA1 (0.54) | LMNAPOLBALOX5KDM4EHPGD | |
| SCHEMBL3970430 | 0.79 | PDE10A (0.42) | CYP3A4LMNAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL8140503 | 0.78 | PDE10A (0.45) | CYP3A4KDRMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL3968161 | 0.76 | PDE10A (0.39) | SMN1; SMN2ALOX5PDE10ACASP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359890-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-6673934-B2 | 4-AMINO-2-(1-ARYLOXY-ETHYL)PHENOL COMPOUND | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359890-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-31 | — | — | US | disclosed |
| WO-2002058631-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | AOX1, CYC1, CBR1 | CYP3A4 266/4885KDR 4471/4885TP53 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.