Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327448 | 0.83 | LMNA (0.61) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL489581 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL14760365 | 0.79 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| Lithium SCHEMBL30522746 | 0.79 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL597490 | 0.79 | LMNA (0.57) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL337646 | 0.79 | LMNA (0.57) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL20212072 | 0.78 | LMNA (0.55) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL7523552 | 0.76 | ELANE (0.61) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL10778741 | 0.76 | HSD17B10 (0.59) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902049-A2 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-26 | — | — | EP | claimed |
| US-20070010514-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-11 | — | — | US | claimed |
| WO-2006136461-A2 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | claimed |
| US-7507784-B2 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-7497970-B2 | Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal | FUJIFILM CORPORATION (JP) | 2009-03-03 | — | — | US | disclosed |
| EP-1320567-B1 | LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS | NASA (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20070228325-A1 | Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal | FUJIFILM CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20050209429-A1 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-09-22 | — | — | US | disclosed |
| US-6939940-B2 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-09-06 | — | — | US | disclosed |
| US-6610216-B2 | Multicolor photopolymerizable compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1320567-A1 | LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS | The Government of the United States of America as represented by the Administrator of the National Aeronautics and Space Adm. (US) | 2003-06-25 | — | — | EP | disclosed |
| US-20030006398-A1 | Optically active compound, photoreactive chiral agent, liquid crystal composition, method for changing helical structure of liquid crystal, method for fixing helical structure of liquid crystal, liquid crystal color filter, optical film, and recording medium | FUJI PHOTO FILM CO., LTD. | 2003-01-09 | — | — | US | disclosed |
| US-20020132933-A1 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2002-09-19 | — | — | US | disclosed |
| WO-2002022706-A1 | LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010514-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, CYP19A1 | LMNA 1568/4885MAPT 4874/4885POLB 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.