Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327448 | 0.83 | LMNA (0.61) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL14775396 | 0.83 | KMT2A (0.45) | LMNAELANEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23185543 | 0.82 | ELANE (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL489581 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL13867888 | 0.79 | BACE1 (0.54) | LMNAMAPTPOLBPKMHSD17B10 | |
| Lithium SCHEMBL30522746 | 0.79 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL14760365 | 0.79 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL337646 | 0.79 | LMNA (0.57) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL21045001 | 0.79 | CYP19A1 (0.42) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025604-A9 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-05-02 | — | — | WO | claimed |
| WO-2024025604-A2 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | claimed |
| CN-116396313-A | Alkenyl borate, and preparation method and application thereof | 中山大学 | 2023-07-07 | — | — | CN | claimed |
| EP-0590557-B1 | Process for preparing acetoxystyrene | BASF AG (DE) | 1996-08-14 | — | — | EP | claimed |
| US-20250326723-A1 | Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly | UNIV NORTHWESTERN (US) | 2025-10-23 | — | — | US | disclosed |
| US-12411409-B2 | Aromatic underlayer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2025-09-09 | — | — | US | disclosed |
| US-12379660-B2 | Adhesion promoting photoresist underlayer composition | DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| US-12099300-B2 | Aromatic underlayer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2024-09-24 | — | — | US | disclosed |
| WO-2024025604-A9 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-05-02 | — | — | WO | disclosed |
| US-11940732-B2 | Coating compositions and methods of forming electronic devices | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2024-03-26 | — | — | US | disclosed |
| CN-114009768-B | Daylily probiotic fermented powder, preparation method and fermented daylily solid beverage thereof | 中国农业大学 | 2024-03-08 | — | — | CN | disclosed |
| WO-2024025604-A2 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | disclosed |
| EP-2099755-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2009-09-16 | — | — | EP | disclosed |
| US-20090099147-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2009-04-16 | — | — | US | disclosed |
| CN-100448914-C | Liquid crystalline thermosets from ester, ester-imide and ester-amide oligomers | NASA (US) | 2009-01-07 | — | — | CN | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| US-20080166299-A1 | Prevent accumulation of amyloid deposits | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080166299-A1 | Prevent accumulation of amyloid deposits | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-07-10 | — | — | US | disclosed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | disclosed |
| CN-1455792-A | Liquid crystalline thermosets from ester, ester-imide and ester-amide oligomers | NASA (US) | 2003-11-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099147-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, PGRMC2 | LMNA 2081/4885MAPT 4871/4885POLB 3120/4885 |
| US-20080166299-A1 | Prevent accumulation of amyloid deposits | APP, IAPP, TTR | LMNA 702/4885MAPT 11/4885POLB 3985/4885 |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | SCD, SCD5, ACACA | LMNA 823/4885MAPT 2813/4885POLB 3269/4885 |
| US-20250326723-A1 | Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly | CRABP2, RARB, RARA | LMNA 4792/4885MAPT 3789/4885POLB 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.