Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.58 |
| ▸ | CA9 | Q16790 | 13/20 | 0.58 |
| ▸ | CA1 | P00915 | 13/20 | 0.58 |
| ▸ | CA12 | O43570 | 11/20 | 0.58 |
| ▸ | CA5A | P35218 | 4/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.58 |
| ▸ | CA6 | P23280 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA3 | P07451 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824639 | 0.82 | GAA (0.54) | CYP2C19KDM4ESMN1; SMN2TSHRKMT2A | |
| SCHEMBL11839666 | 0.82 | CA2 (0.57) | CA2CA9CA1CA12CA5A | |
| SCHEMBL10916595 | 0.80 | ENPP2 (0.54) | — | |
| SCHEMBL565221 | 0.80 | LMNA (0.50) | KDM4ESMN1; SMN2TSHRTDP1 | |
| SCHEMBL12652094 | 0.80 | CA2 (0.67) | CA2CA9CA1CA12CA5A | |
| SCHEMBL284012 | 0.80 | CA2 (0.73) | CA2CA9CA1CA12CA5A | |
| SCHEMBL11670825 | 0.78 | LMNA (0.48) | KDM4ESMN1; SMN2TSHRTDP1 | |
| Potassium Ion SCHEMBL18916927 | 0.78 | LMNA (0.38) | CA2CA9CA1CA12CA5A | |
| SCHEMBL11670818 | 0.78 | LMNA (0.42) | CA2CA9CA1CA12SMN1; SMN2 | |
| SCHEMBL11050677 | 0.78 | ALDH1A1 (0.44) | CA2CA9CA1CA12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391884-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-11-28 | — | — | US | disclosed |
| US-12084424-B2 | Compounds and compositions for treating conditions associated with NLRP activity | NOVARTIS AG (CH) | 2024-09-10 | — | — | US | disclosed |
| EP-4349820-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | Novartis AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| EP-3658539-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| CN-111094242-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-20230416211-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-12-28 | — | — | US | disclosed |
| CN-117209447-A | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117143042-A | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-111094243-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-20080233516-A1 | NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| EP-1972440-A2 | Negative lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM Corporation (JP) | 2008-09-24 | — | — | EP | disclosed |
| US-6517987-B2 | Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| US-20010041299-A1 | Positive-working presensitized plate useful for preparing a lithographic printing plate | FUJIFILM CORPORATION (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0671660-B1 | Lead-frame forming material | FUJI PHOTO FILM CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-1077392-A1 | Photosensitive lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5670293-A | LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0330239-B1 | Photosensitive composition | FUJI PHOTO FILM CO LTD (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0671660-A2 | Lead-frame forming material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5141838-A | Lithography printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12084424-B2 | Compounds and compositions for treating conditions associated with NLRP activity | NLRP1, NLRP3, NOD1 | CA2 1245/4885CA9 3039/4885CA1 3665/4885 |
| US-20230416211-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | CA2 1245/4885CA9 3039/4885CA1 3665/4885 |
| US-20240391884-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | CA2 1245/4885CA9 3039/4885CA1 3665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.