Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973824 | 0.88 | HTR2A (0.36) | ALDH1A1KDRCNR2LY96 | |
| SCHEMBL3974167 | 0.84 | BCHE (0.39) | MAOBACHECNR2BCHE | |
| SCHEMBL3972272 | 0.83 | CA1 (0.38) | ALDH1A1ACHEBCHE | |
| SCHEMBL3973494 | 0.83 | IDH1 (0.39) | ALDH1A1KDM4EHPGDCYP3A4CNR2 | |
| SCHEMBL3979222 | 0.80 | CNR2 (0.34) | ALDH1A1KDM4EEGFRACHECNR2 | |
| SCHEMBL3973213 | 0.80 | HTR2A (0.42) | KDM4EKDRCYP3A4CYP2D6THPO | |
| SCHEMBL3974146 | 0.79 | CYP3A4 (0.37) | ALDH1A1KDM4EHPGDRAB9AEGFR | |
| SCHEMBL3974894 | 0.79 | HTR2A (0.44) | KDRMAOBACHECYP3A4CYP2D6 | |
| SCHEMBL4084541 | 0.78 | SYK (0.45) | ALDH1A1KDM4EHPGDKDRCYP2D6 | |
| SCHEMBL3973411 | 0.78 | CNR2 (0.45) | ALDH1A1ACHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |