Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021999 | 0.90 | MMP2 (0.63) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13588576 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31310982 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6323678 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4107256 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31310984 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6323675 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12169286 | 0.83 | CA2 (0.75) | SMN1; SMN2ALDH1A1CA12CA9CA2 | |
| SCHEMBL11650680 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16197361 | 0.82 | TDP1 (0.55) | SMN1; SMN2ALDH1A1LMNAMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699028-A | It is substituted 4- phenylpyridine compounds as non-systemic TGR5 agonists | 阿德利克斯公司 | 2018-10-23 | — | — | CN | claimed |
| US-8354407-B2 | 2-anilino-4-(heterocyclic)amino-pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-15 | — | — | US | claimed |
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-10 | — | — | US | claimed |
| CN-101506175-A | 2-anilino-4-(heterocyclic)amino-pyrimidines as inhibitors of protein kinase C-alpha | BOEHRINGER INGELHEIM INT (DE) | 2009-08-12 | — | — | CN | claimed |
| US-20070293494-A1 | 2-Anilino-4-(Heterocyclic) Amino-Pyrimidines | DJUNG JANE F | 2007-12-20 | — | — | US | claimed |
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
| CN-108699028-A | It is substituted 4- phenylpyridine compounds as non-systemic TGR5 agonists | 阿德利克斯公司 | 2018-10-23 | — | — | CN | disclosed |
| US-9726932-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2017-08-08 | — | — | US | disclosed |
| US-9726932-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2017-08-08 | — | — | US | disclosed |
| US-20160231606-A1 | OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | FUJIFILM CORPORATION (JP) | 2016-08-11 | — | — | US | disclosed |
| US-9354356-B2 | Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same | FUJIFILM CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-9348177-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2016-05-24 | — | — | US | disclosed |
| US-20070285603-A1 | Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It | FUJI PHOTO FILM CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070273815-A1 | Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070259134-A1 | Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |
| US-20070195226-A1 | Polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070182895-A1 | Liquid crystal display device | FUJI PHOTO FILM CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070076155-A1 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-20070059458-A1 | Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| US-6953788-B1 | 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293494-A1 | 2-Anilino-4-(Heterocyclic) Amino-Pyrimidines | PRKCA, PRKCG, PRKCH | SMN1; SMN2 3836/4885ALDH1A1 4216/4885CYP1A2 3383/4885 |
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | SMN1; SMN2 991/4885ALDH1A1 2269/4885CYP1A2 4623/4885 |
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | PRKCA, PRKCG, PRKCH | SMN1; SMN2 3836/4885ALDH1A1 4216/4885CYP1A2 3383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.