Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973960 | 0.84 | KDM4E (0.38) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL28242027 | 0.69 | KMO (0.40) | LMNA | |
| SCHEMBL3996013 | 0.68 | KDR (0.41) | ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL6525636 | 0.66 | KMO (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3973747 | 0.66 | KMT2A (0.44) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL3992240 | 0.65 | POLB (0.38) | ALDH1A1LMNAPOLB | |
| SCHEMBL3653195 | 0.64 | SMN1; SMN2 (0.47) | ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL3979300 | 0.63 | CDK2 (0.36) | ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL3990181 | 0.63 | RORC (0.39) | POLB | |
| SCHEMBL3972624 | 0.63 | POLB (0.55) | ALDH1A1LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |