Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 6/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714383 | 0.93 | CALM1 (0.61) | HTTCALM1CA2NPC1POLB | |
| SCHEMBL579760 | 0.93 | CALM1 (0.61) | HTTCALM1CA2NPC1POLB | |
| SCHEMBL697888 | 0.90 | HTT (0.61) | HTTCALM1PDE4APDE4DNPC1 | |
| Alcohol SCHEMBL8946306 | 0.86 | CA2 (0.63) | CA2NPC1POLBRAB9AKDM4E | |
| SCHEMBL119395 | 0.86 | CA2 (0.68) | CA2NPC1POLBRAB9AKDM4E | |
| SCHEMBL28170408 | 0.86 | CA2 (0.68) | CA2NPC1POLBRAB9AKDM4E | |
| SCHEMBL29997296 | 0.86 | CA2 (0.68) | CA2NPC1POLBRAB9AKDM4E | |
| SCHEMBL6798353 | 0.86 | NPSR1 (0.50) | CA2NPC1POLBRAB9AMAPT | |
| SCHEMBL11030253 | 0.85 | CALM1 (0.56) | L3MBTL1CALM1CA2PDE4APDE4B | |
| SCHEMBL7928047 | 0.84 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910260-B1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA SPA (IT) | 2009-12-16 | — | — | EP | claimed |
| US-7544843-B2 | Process for preparing 3,4-dioxo-substituted aromatic aldehydes | ENDURA S.P.A. (IT) | 2009-06-09 | — | — | US | claimed |
| US-20090062569-A1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA S.P.A. (IT) | 2009-03-05 | — | — | US | claimed |
| EP-1910260-A1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA S.p.A. (IT) | 2008-04-16 | — | — | EP | claimed |
| WO-2007012641-A1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA S.P.A. (IT) | 2007-02-01 | — | — | WO | claimed |
| US-6319310-B1 | FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE | XEROX CORPORATION | 2001-11-20 | — | — | US | claimed |
| EP-0674232-B1 | Recording sheets | XEROX CORP (US) | 2000-05-31 | — | — | EP | claimed |
| US-5663022-A | Recording sheets | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| US-5663029-A | DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0674232-A2 | Recording sheets | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| US-11008288-B1 | Methods for preparation of apremilast | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2021-05-18 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-1910260-B1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA SPA (IT) | 2009-12-16 | — | — | EP | disclosed |
| US-7544843-B2 | Process for preparing 3,4-dioxo-substituted aromatic aldehydes | ENDURA S.P.A. (IT) | 2009-06-09 | — | — | US | disclosed |
| US-20090062569-A1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | ENDURA S.P.A. (IT) | 2009-03-05 | — | — | US | disclosed |
| US-6106601-A | MIXTURE CONTAINING OXAZOLINE AND THIOUREA COMPOUNDS | XEROX CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| US-6071333-A | Ink compositions | XEROX CORPORATION (US) | 2000-06-06 | — | — | US | disclosed |
| US-6066200-A | COMPRISING A SOLID UREA COMPOUND, AN ALCOHOL, A LIGHTFASTNESS COMPONENT, A LIGHTFAST ANTIOXIDANT, AND A COLORANT | XEROX CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| US-5922117-A | Ink compositions containing alcohols | XEROX CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| US-5663029-A | DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062569-A1 | PROCESS FOR PREPARING 3,4-DIOXO-SUBSTITUTED AROMATIC ALDEHYDES | HAAO, AOX1, ADH1A | L3MBTL1 4479/4885HTT 1989/4885CALM1 4590/4885 |
| US-11008288-B1 | Methods for preparation of apremilast | APRT, ALDH3A1, TPMT | L3MBTL1 4801/4885HTT 1944/4885CALM1 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.