Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052882 | 0.86 | KEAP1 (0.43) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1270991 | 0.85 | ALDH1A1 (0.37) | POLBMEN1KMT2AALDH1A1ESR1 | |
| SCHEMBL64191 | 0.84 | HTT (0.43) | MEN1KMT2AALDH1A1ATMCYP1A2 | |
| SCHEMBL8073829 | 0.83 | PPARA (0.37) | POLBMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL5707382 | 0.83 | ALDH1A1 (0.36) | POLBMEN1KMT2AALDH1A1CYP2C19 | |
| Trifluoromethanesulfonic Acid SCHEMBL64774 | 0.82 | GPR3 (0.37) | MEN1KMT2AALDH1A1HSD11B1KEAP1 | |
| SCHEMBL248257 | 0.81 | KIF11 (0.40) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| Trifluoromethanesulfonic Acid SCHEMBL3161572 | 0.80 | HSD11B1 (0.40) | POLBMEN1KMT2AALDH1A1ESR1 | |
| SCHEMBL7733544 | 0.79 | NR3C2 (0.43) | POLBMEN1KMT2AALDH1A1ESR1 | |
| SCHEMBL175822 | 0.79 | HSD11B1 (0.43) | ALDH1A1HSD11B1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018271-A2 | PHOTOIMAGEABLE NOZZLE MEMBERS AND METHODS RELATING THERETO | Lexmark International, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007041176-A2 | PHOTOIMAGEABLE NOZZLE MEMBERS AND METHODS RELATING THERETO | LEXMARK INTERNATIONAL, INC. (US) | 2007-04-12 | — | — | WO | disclosed |