SCHEMBL397357

SCHEMBL397357

C=C(Cc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
MAPT P10636 2/20 0.56
HPGD P15428 1/20 0.56
LMNA P02545 2/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
GAA P10253 1/20 0.54
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GHSR Q92847 1/20 0.53
HDAC1 Q13547 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
POLB P06746 1/20 0.52
GFER P55789 1/20 0.52
LIMK2 P53671 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396740 0.87 HDAC1 (0.59) ALDH1A1LMNACA12CA1CA2
SCHEMBL397676 0.87 HDAC1 (0.68) ALDH1A1LMNACA12CA1CA2
SCHEMBL8074277 0.86 ALDH1A1 (0.74) ALDH1A1MAPTHPGDLMNACA12
SCHEMBL396993 0.85 ALDH1A1 (0.58) ALDH1A1CA12CA1CA2CA9
SCHEMBL2691033 0.81 HDAC1 (0.74) ALDH1A1MAPTHPGDLMNAMEN1
SCHEMBL2693160 0.81 ALDH1A1 (0.63) ALDH1A1MAPTHPGDLMNAMEN1
SCHEMBL1921797 0.81 CTBP2 (0.56) ALDH1A1HPGDLMNAMEN1KMT2A
SCHEMBL397628 0.80 HPGD (0.56) ALDH1A1HPGDLMNARECQLSMN1; SMN2
SCHEMBL395695 0.80 SMN1; SMN2 (0.46) ALDH1A1HPGDLMNACA12CA1
SCHEMBL396811 0.80 LMNA (0.62) ALDH1A1LMNAMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed