Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396740 | 0.94 | HDAC1 (0.59) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL397357 | 0.87 | ALDH1A1 (0.64) | HDAC1HDAC8HDAC4MEN1KMT2A | |
| SCHEMBL396811 | 0.86 | LMNA (0.62) | HDAC1HDAC8HDAC4MEN1KMT2A | |
| SCHEMBL5202198 | 0.85 | HDAC1 (0.71) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL396990 | 0.85 | HTR6 (0.59) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL396887 | 0.85 | HTR6 (0.62) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL5205017 | 0.84 | HDAC1 (0.75) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL14812106 | 0.81 | HDAC8 (1.00) | HDAC1HDAC8HDAC4HTR6MEN1 | |
| SCHEMBL397628 | 0.80 | HPGD (0.56) | ALDH1A1KEAP1LMNAAR | |
| SCHEMBL398078 | 0.79 | HPGD (0.57) | HDAC1HDAC8ALDH1A1LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |