SCHEMBL396740

SCHEMBL396740

C=C(Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
ALDH1A1 P00352 3/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
PKM P14618 1/20 0.56
IL1RN P18510 1/20 0.54
KEAP1 Q14145 1/20 0.54
ERAP1 Q9NZ08 1/20 0.54
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
LMNA P02545 1/20 0.53
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
LIMK2 P53671 4/20 0.50
LIMK1 P53667 2/20 0.50
HDAC4 P56524 1/20 0.50
GHSR Q92847 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ABL1 P00519 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397676 0.94 HDAC1 (0.68) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL397357 0.87 ALDH1A1 (0.64) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL396811 0.86 LMNA (0.62) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL396990 0.85 HTR6 (0.59) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL396887 0.85 HTR6 (0.62) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL27889027 0.84 ALDH1A1 (0.67) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL396993 0.80 ALDH1A1 (0.58) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL395695 0.80 SMN1; SMN2 (0.46) ALDH1A1CA12CA9LMNACA1
SCHEMBL5202198 0.79 HDAC1 (0.71) HDAC1HDAC8ALDH1A1KMT2AMEN1
SCHEMBL5205017 0.78 HDAC1 (0.75) HDAC1HDAC8ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed