Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393833 | 0.88 | AKR1C3 (0.61) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL396740 | 0.86 | HDAC1 (0.59) | LMNAALDH1A1KMT2AMEN1GAA | |
| SCHEMBL397676 | 0.86 | HDAC1 (0.68) | LMNAALDH1A1KMT2AMEN1HDAC1 | |
| SCHEMBL397357 | 0.80 | ALDH1A1 (0.64) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL396887 | 0.80 | HTR6 (0.62) | ALDH1A1KMT2AMEN1GAAHDAC1 | |
| SCHEMBL2614387 | 0.78 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8248238 | 0.78 | HDAC1 (0.71) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7445814 | 0.77 | ALOX5 (0.53) | KMT2AMEN1 | |
| SCHEMBL397718 | 0.76 | LMNA (0.56) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL396993 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1GAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |