Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129167 | 0.82 | TSHR (0.47) | KMT2AAPEX1TSHRHTTBCAT2 | |
| SCHEMBL14839314 | 0.81 | HPGD (0.55) | KMT2ATSHRHTTKDM4EHPGD | |
| SCHEMBL6903284 | 0.80 | TSHR (0.58) | KMT2AAPEX1TSHRHTTKDM4E | |
| SCHEMBL9329299 | 0.77 | TSHR (0.46) | KMT2AAPEX1TSHRHTTBCAT2 | |
| SCHEMBL6566957 | 0.77 | TSHR (0.55) | KMT2AAPEX1TSHRHTTKDM4E | |
| SCHEMBL6075765 | 0.77 | TSHR (0.46) | KMT2AAPEX1TSHRHTTBCAT2 | |
| SCHEMBL461826 | 0.76 | HPGD (0.66) | KMT2AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7870127 | 0.76 | HPGD (0.66) | KMT2AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL1628440 | 0.76 | GAA (0.63) | HPGDALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL31448014 | 0.75 | KEAP1 (0.62) | KMT2AAPEX1TSHRHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923436-B1 | Powder compositions comprising Beta-Hydroxyalkyl amides from the ring-opening of acidic coumpounds | ROHM & HAAS (US) | 2009-01-21 | — | — | EP | disclosed |
| EP-1923436-A1 | Powder compositions comprising Beta-Hydroxyalkyl amides from the ring-opening of acidic coumpounds | Rohm and Haas Company (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20080114132-A1 | Powder compositions comprising beta-hydroxyalkyl amides from the ring-opening of acidic compounds | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2008-05-15 | — | — | US | disclosed |