Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974076 | 0.90 | MAPT (0.62) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3979943 | 0.86 | PRKCZ (0.61) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3980970 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3976253 | 0.80 | PRKCZ (0.50) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3976445 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3975112 | 0.80 | PRKCZ (0.50) | ALDH1A1MAPTMEN1KMT2APRKCZ | |
| SCHEMBL8290552 | 0.79 | MAPT (1.00) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL3975901 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MAPTMAPK1HDAC2MEN1 | |
| SCHEMBL3980569 | 0.77 | ADORA1 (0.61) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31657792 | 0.74 | POLB (0.73) | ALDH1A1MAPTMAPK1HDAC2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |