Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975612 | 0.85 | MAPT (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2HCRTR1 | |
| SCHEMBL3980428 | 0.83 | GAA (0.40) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL447466 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL448440 | 0.79 | MEN1 (0.44) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3972272 | 0.79 | CA1 (0.38) | ALDH1A1GAACA1CA2CA4 | |
| SCHEMBL3973411 | 0.76 | CNR2 (0.45) | ALDH1A1 | |
| SCHEMBL3973494 | 0.76 | IDH1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL3973392 | 0.75 | CA1 (0.35) | CA1CA2CA4CA6 | |
| SCHEMBL3973824 | 0.74 | HTR2A (0.36) | ALDH1A1SMN1; SMN2CA1CA2CA4 | |
| SCHEMBL743175 | 0.73 | MAPK14 (0.39) | MEN1KMT2ALMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |