Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975612 | 0.88 | MAPT (0.43) | GAAMEN1KMT2ASMN1; SMN2DHPS | |
| SCHEMBL447466 | 0.83 | ALDH1A1 (0.41) | TDP1MEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL3974440 | 0.83 | ALDH1A1 (0.39) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL448440 | 0.82 | MEN1 (0.44) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3972272 | 0.80 | CA1 (0.38) | GAAIDH1 | |
| SCHEMBL3973411 | 0.77 | CNR2 (0.45) | — | |
| SCHEMBL3973494 | 0.77 | IDH1 (0.39) | GAAPOLBTDP1MEN1KMT2A | |
| SCHEMBL3973392 | 0.76 | CA1 (0.35) | — | |
| SCHEMBL3973824 | 0.75 | HTR2A (0.36) | TDP1SMN1; SMN2 | |
| SCHEMBL449975 | 0.74 | HDAC1 (0.61) | HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |