SCHEMBL3974543

SCHEMBL3974543

CC(O)[C@H]1COC(C)(C)O1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11961352 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL1487007 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL765807 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL8520973 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL345859 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL11961353 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL345858 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL366852 1.00 L3MBTL1 (0.33) L3MBTL1CA2
SCHEMBL16730247 0.84 CA2 (0.32) CA2
SCHEMBL3016063 0.84 CA2 (0.32) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263408-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2025-08-21 US disclosed
EP-4263492-B1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARM INC (US) 2025-04-09 EP disclosed
EP-4504724-A1 SPLEEN TYROSINE KINASE INHIBITORS Uniquest Pty Limited (AU) 2025-02-12 EP disclosed
CN-119325474-A Spleen tyrosine kinase inhibitors 尤尼奎斯特公司 2025-01-17 CN disclosed
US-20240132450-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARMACEUTICALS INC. 2024-04-25 US disclosed
WO-2023193054-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2023-10-12 WO disclosed
WO-2022150707-A1 FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF Tabomedex Biosciences, Inc. (US) 2022-07-14 WO disclosed
CN-102796081-A Pyrimidine sulphonamide derivatives as chemokine receptor modulators ASTRAZENECA AB 2012-11-28 CN disclosed
CN-101048401-B Pyrimidine sulfonamide derivatives as chemokine receptor modulators ASTRAZENECA AB 2012-09-12 CN disclosed
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-01 US disclosed
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-01 US disclosed
US-7534742-B2 Isoprenoid biosynthesis EISENREICH WOLFGANG 2009-05-19 US disclosed
WO-2008032858-A2 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-20 WO disclosed
EP-1895008-A2 Isoprenoid biosynthesis Bacher, Adelbert (DE) 2008-03-05 EP disclosed
CN-101048401-A Pyrimidine sulfonamide derivatives as chemokine receptor modulators ASTRAZENECA AB (SE) 2007-10-03 CN disclosed
EP-1198575-B1 ISOPRENOID BIOSYNTHESIS BACHER ADELBERT (DE) 2007-09-19 EP disclosed
US-20070015216-A1 Isoprenoid biosynthesis EISENREICH WOLFGANG 2007-01-18 US disclosed
US-7122331-B1 Isoprenoid biosynthesis EISENREICH WOLFGANG 2006-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132450-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 GPR88, GPR65, GPR68 L3MBTL1 3949/4885CA2 4832/4885
US-20250263408-A1 SPLEEN TYROSINE KINASE INHIBITORS LCK, BTK, SYK L3MBTL1 2674/4885CA2 2634/4885
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF NR2C2, NR4A3, NR0B2 L3MBTL1 818/4885CA2 3688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.