Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4087801 | 0.99 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 | |
| SCHEMBL11836098 | 0.82 | KDM4E (0.58) | SMN1; SMN2ALDH1A1ALOX15TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL11837410 | 0.81 | KDM4E (0.57) | SMN1; SMN2ALDH1A1ALOX15TSHRKMT2A | |
| SCHEMBL8243795 | 0.81 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 | |
| SCHEMBL8559004 | 0.80 | RAB9A (0.65) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 | |
| SCHEMBL4086446 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 | |
| SCHEMBL8555258 | 0.79 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 | |
| Talastine SCHEMBL30502 | 0.78 | ADRA1A (0.81) | TSHRMEN1KMT2ACYP1A2CYP3A4 | |
| Talastine SCHEMBL29350005 | 0.78 | ADRA1A (0.81) | TSHRMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL31703144 | 0.76 | ALOX15 (1.00) | SMN1; SMN2ALDH1A1ALOX15TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051504-A1 | BENZO- AND PYRIDOPYRIDAZINONES WITH ANALGESIC AND ANTIINFLAMMATORY ACTIVITY | UNIWERSYTET LODSKI (PL) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009051504-A1 | BENZO- AND PYRIDOPYRIDAZINONES WITH ANALGESIC AND ANTIINFLAMMATORY ACTIVITY | UNIWERSYTET LODSKI (PL) | 2009-04-23 | — | — | WO | disclosed |