Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 3/20 | 0.42 |
| ▸ | RHOA | P61586 | 3/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972275 | 0.89 | RORB (0.49) | ADORA1PRKCZRORBANO1MEN1 | |
| SCHEMBL3974068 | 0.87 | CNR2 (0.51) | ADORA1PRKCZRORBMEN1KMT2A | |
| SCHEMBL3974360 | 0.82 | PRKCZ (0.62) | ADORA1PRKCZANO1MEN1RAB9A | |
| SCHEMBL3972589 | 0.79 | PRKCZ (0.55) | ADORA1PRKCZANO1MEN1RAB9A | |
| SCHEMBL3972011 | 0.79 | PRKCZ (0.57) | ADORA1PRKCZANO1MEN1RAB9A | |
| SCHEMBL3975200 | 0.78 | PRKCZ (0.48) | ADORA1PRKCZRORBMEN1RAB9A | |
| SCHEMBL9720150 | 0.78 | ALDH1A1 (0.53) | ADORA1PRKCZMEN1RAB9AKMT2A | |
| SCHEMBL3980569 | 0.78 | ADORA1 (0.61) | ADORA1PRKCZRORBMEN1KMT2A | |
| SCHEMBL3980156 | 0.78 | PRKCZ (0.45) | ADORA1PRKCZANO1MEN1RAB9A | |
| SCHEMBL3976906 | 0.76 | PRKCZ (0.55) | ADORA1PRKCZANO1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |