Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980569 | 0.90 | ADORA1 (0.61) | CNR2CNR1ADORA1MEN1ALDH1A1 | |
| SCHEMBL3975701 | 0.87 | ADORA1 (0.50) | ADORA1MEN1KMT2APRKCZLMNA | |
| SCHEMBL9720150 | 0.85 | ALDH1A1 (0.53) | ADORA1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL3980970 | 0.81 | ALDH1A1 (0.65) | ADORA1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL3972275 | 0.79 | RORB (0.49) | CNR2ADORA1MEN1ALDH1A1KMT2A | |
| SCHEMBL3976339 | 0.78 | PRKCZ (0.58) | MEN1ALDH1A1KMT2APRKCZLMNA | |
| SCHEMBL3976253 | 0.77 | PRKCZ (0.50) | ADORA1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL12466271 | 0.77 | ADORA1 (0.49) | ADORA1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL3974317 | 0.75 | PRKCZ (0.54) | ADORA1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL3981694 | 0.75 | PRKCZ (0.62) | MEN1ALDH1A1KMT2APRKCZLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |