Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977299 | 0.73 | FDPS (0.63) | FDPSADORA2A | |
| SCHEMBL21311152 | 0.67 | ADORA2A (0.40) | ADORA2AADORA1 | |
| SCHEMBL2063606 | 0.61 | ADORA2A (0.64) | FDPSADORA2AADORA1DNMT3A | |
| SCHEMBL21363628 | 0.58 | ADORA2A (0.35) | ADORA2AADORA1 | |
| SCHEMBL3476218 | 0.57 | ADORA2A (0.47) | ADORA2A | |
| SCHEMBL9544785 | 0.57 | FPR2 (0.37) | ADORA2ADNMT3A | |
| SCHEMBL3984337 | 0.56 | FDPS (0.51) | FDPS | |
| SCHEMBL22533664 | 0.56 | HDAC6 (0.38) | ADORA2A | |
| SCHEMBL28384395 | 0.55 | FDPS (0.47) | FDPS | |
| SCHEMBL4815868 | 0.53 | ADORA2A (0.75) | ADORA2AADORA1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |