Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070876 | 0.95 | LSS (0.63) | SIGMAR1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL10921447 | 0.89 | SIGMAR1 (0.59) | SIGMAR1LMNAALDH1A1KDM4ELSS | |
| SCHEMBL10502663 | 0.84 | SIGMAR1 (0.68) | SIGMAR1ALDH1A1KDM4ELSSMEN1 | |
| SCHEMBL5878453 | 0.83 | PKM (0.57) | ALDH1A1KDM4EPKMMEN1KMT2A | |
| SCHEMBL16122104 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1HPGDPKMMEN1 | |
| SCHEMBL12504054 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1KDM4EHPGDPKM | |
| SCHEMBL21550461 | 0.83 | DUSP3 (0.60) | LMNAALDH1A1KDM4EHPGDPKM | |
| SCHEMBL17976330 | 0.83 | LMNA (0.68) | SIGMAR1LMNAALDH1A1HPGDPKM | |
| Hydrochloric Acid SCHEMBL10503565 | 0.82 | SIGMAR1 (0.66) | SIGMAR1ALDH1A1KDM4ELSSMEN1 | |
| SCHEMBL10603688 | 0.82 | SIGMAR1 (0.66) | SIGMAR1ALDH1A1KDM4ELSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062036-A2 | PROCESSES FOR PREPARING LEVOCETIRIZINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-05-14 | — | — | WO | disclosed |
| EP-0050396-B1 | COUMARIN INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-12-27 | — | — | EP | disclosed |
| EP-0010392-B1 | HETEROCYCLIC COUMARIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVES | BEECHAM GROUP PLC (GB) | 1982-12-29 | — | — | EP | disclosed |
| EP-0050396-A1 | Coumarin intermediates | BEECHAM GROUP PLC (GB) | 1982-04-28 | — | — | EP | disclosed |