Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969250 | 0.80 | ADRA2A (0.44) | ALDH1A1 | |
| SCHEMBL3972855 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2PLAUMAOAIDO1KMT2A | |
| SCHEMBL8611486 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2PLAUKMT2AKDM4EALDH1A1 | |
| SCHEMBL8611160 | 0.66 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL3893897 | 0.64 | ENPP2 (0.44) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14093102 | 0.64 | MLYCD (0.45) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL3896543 | 0.63 | LPL (0.52) | SMN1; SMN2PLAUALDH1A1HPGDTAAR1 | |
| SCHEMBL12304289 | 0.63 | LPL (0.52) | SMN1; SMN2PLAUALDH1A1HPGDTAAR1 | |
| SCHEMBL4828364 | 0.63 | SMN1; SMN2 (1.00) | SMN1; SMN2PLAUMAOAIDO1KMT2A | |
| SCHEMBL20269203 | 0.63 | SMN1; SMN2 (0.61) | SMN1; SMN2PLAUMAOAIDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016061-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | Glaxo Group Limited (GB) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007122241-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |