Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | RXRA | P19793 | 7/20 | 0.36 |
| ▸ | RARA | P10276 | 7/20 | 0.36 |
| ▸ | RARG | P13631 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034537 | 0.83 | CYP1A2 (0.49) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL9342959 | 0.82 | CYP1A2 (0.51) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL1782075 | 0.82 | CYP1A2 (0.47) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL9838256 | 0.80 | CYP1A2 (0.46) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL17129798 | 0.77 | CYP1A2 (0.44) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL7171679 | 0.77 | CYP1A2 (0.44) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL12160497 | 0.77 | CYP1A2 (0.44) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL15609811 | 0.76 | CYP1A2 (0.46) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL14879901 | 0.76 | CYP1A2 (0.46) | CYP1A2HAO1RARBALDH1A1RXRA | |
| SCHEMBL11448119 | 0.74 | CYP1A2 (0.45) | CYP1A2HAO1RARBALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402969-A | 3-acyl-ingenol II | LEO PHARMA AS | 2013-11-20 | — | — | CN | disclosed |
| EP-2655312-A1 | 3-ACYL-INGENOLS II | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012083954-A1 | 3-ACYL-INGENOLS II | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | disclosed |
| US-7534541-B2 | Heterocycle-hydrazone based charge transport materials | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-05-19 | — | — | US | disclosed |
| US-7427460-B2 | Hydrazone-based charge transport materials having an ethylenically unsaturated group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-09-23 | — | — | US | disclosed |
| US-7378203-B2 | Ferrocene(di)carboxaldehyde N-phenylhydrazone and monomeric, bridged or polymeric derivatives; good mechanical and electrostatic properties; can be used with liquid and dry toners to produce high quality images; imaging systems can be maintained after repeated cycling; electrography | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-05-27 | — | — | US | disclosed |
| US-7371493-B2 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-05-13 | — | — | US | disclosed |
| US-7364825-B2 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-29 | — | — | US | disclosed |
| US-7344811-B2 | Polysilane-based charge transport materials | SAMSUNG ELECTRONIC CO., LTD. (KR) | 2008-03-18 | — | — | US | disclosed |
| US-7316878-B2 | Hydrazone-based charge transport materials having an unsaturated acyl group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-08 | — | — | US | disclosed |
| US-20060210897-A1 | Charge transport materials having at least a metallocene group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-09-21 | — | — | US | disclosed |
| US-20060204875-A1 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-09-14 | — | — | US | disclosed |
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-08-10 | — | — | US | disclosed |
| US-20060166118-A1 | Heterocycle-hydrazone based charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-07-27 | — | — | US | disclosed |
| US-20060093933-A1 | Polysilane-based charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-05-04 | — | — | US | disclosed |
| US-20060046171-A1 | Hydrazone-based charge transport materials having an unsaturated acyl group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-03-02 | — | — | US | disclosed |
| US-20060024598-A1 | Hydrazone-based charge transport materials having an ethylenically unsaturated group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-02-02 | — | — | US | disclosed |
| US-4900870-A | Process for the preparation of cycloaliphatic ketones | FIRMENICH S.A. (CH) | 1990-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166118-A1 | Heterocycle-hydrazone based charge transport materials | AQP1, SLC9B2, SLC9A2 | CYP1A2 1188/4885HAO1 392/4885RARB 302/4885 |
| US-20060204875-A1 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | TSPO, SLC43A1, LMNB2 | CYP1A2 1533/4885HAO1 245/4885RARB 4119/4885 |
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SLC1A2, SLC9B2, SLC6A19 | CYP1A2 1342/4885HAO1 440/4885RARB 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.