Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 5/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841082 | 0.87 | MLYCD (0.44) | TRPV1NPC1 | |
| SCHEMBL14281215 | 0.79 | MEN1 (0.52) | MAPTTRPV1ABL1NPC1RAB9A | |
| SCHEMBL13702138 | 0.78 | MLYCD (0.65) | TRPV1NPC1RAB9A | |
| SCHEMBL3973134 | 0.76 | ABL1 (0.49) | TRPV1ABL1NTRK1 | |
| SCHEMBL5273573 | 0.73 | TRPV1 (0.49) | TRPV1NPC1RAB9A | |
| SCHEMBL4664426 | 0.73 | KDM4E (0.51) | TRPV1NPC1RAB9A | |
| SCHEMBL30523236 | 0.69 | TRPV1 (0.52) | MAPTTRPV1NPC1RAB9A | |
| SCHEMBL30827436 | 0.69 | MAPT (0.44) | MAPTTRPV1ABL1NPC1RAB9A | |
| SCHEMBL28357516 | 0.68 | MAPT (0.58) | MAPTTRPV1NPC1RAB9A | |
| SCHEMBL25367889 | 0.68 | TRPV1 (0.46) | MAPTTRPV1ABL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560564-B2 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | ANNIS GARY D | 2006-09-14 | — | — | US | disclosed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, C1S | MAPT 4481/4885TRPV1 449/4885ABL1 1997/4885 |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, DDC | MAPT 4355/4885TRPV1 450/4885ABL1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.