SCHEMBL3973134

SCHEMBL3973134

Cc1cncc(C(=O)NC(C)C)c1NC(=O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.49
TRPV1 Q8NER1 4/20 0.46
SCN10A Q9Y5Y9 1/20 0.46
NTRK1 P04629 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4080343 0.84 MAPT (0.56) ABL1TRPV1SCN10A
SCHEMBL4664426 0.84 KDM4E (0.51) TRPV1
SCHEMBL13702138 0.78 MLYCD (0.65) TRPV1
SCHEMBL3981465 0.76 MAPT (0.49) ABL1TRPV1NTRK1
SCHEMBL1381716 0.71 KDM4E (0.54) TRPV1
SCHEMBL5273573 0.70 TRPV1 (0.49) TRPV1
SCHEMBL3191191 0.70 LMNA (0.48) TRPV1
SCHEMBL31560013 0.69 SMN1; SMN2 (0.56) TRPV1
SCHEMBL23657478 0.68 KDM4E (0.67) TRPV1
SCHEMBL27913694 0.68 PDE2A (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560564-B2 Heterocyclic diamide invertebrate pest control agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-14 US disclosed
US-20060205748-A1 Heterocyclic diamide invertebrate pest control agents ANNIS GARY D 2006-09-14 US disclosed
US-20040102324-A1 Heterocyclic diamide invertebrate pest control agents E.I. DU PONT DE NEMOURS AND COMPANY 2004-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205748-A1 Heterocyclic diamide invertebrate pest control agents DDT, DBF4, C1S ABL1 1997/4885TRPV1 449/4885SCN10A 866/4885
US-20040102324-A1 Heterocyclic diamide invertebrate pest control agents DDT, DBF4, DDC ABL1 2770/4885TRPV1 450/4885SCN10A 921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.