Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025375 | 0.81 | HTR7 (0.55) | HTR7TSHRACHEHTR1ANPC1 | |
| SCHEMBL278217 | 0.81 | S1PR4 (0.53) | S1PR4TSHRACHENPC1HPGD | |
| SCHEMBL11079208 | 0.80 | HTR7 (0.44) | HTR7TSHRACHECA1CA2 | |
| SCHEMBL27720563 | 0.78 | METAP2 (0.46) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL29535942 | 0.78 | HDAC7 (0.50) | S1PR4ALDH1A1HPGDMETAP2KDM4E | |
| SCHEMBL277849 | 0.78 | HDAC7 (0.50) | S1PR4ALDH1A1HPGDMETAP2KDM4E | |
| SCHEMBL19577768 | 0.78 | MAPT (0.48) | HTR7TSHRACHEHTR1ANPC1 | |
| SCHEMBL29628983 | 0.77 | HTR7 (0.60) | HTR7TSHRACHECA1CA2 | |
| SCHEMBL19577765 | 0.77 | HTR7 (0.60) | HTR7TSHRACHECA1CA2 | |
| SCHEMBL598686 | 0.75 | TSHR (0.53) | TSHRACHENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299405-B1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-13 | — | — | EP | disclosed |
| CN-100436490-C | Polymerization catalyst for alpha-olefin, novel transition metal compound and catalyst component, and process for producing polymer | MITSUBISHI CHEM CORP (JP) | 2008-11-26 | — | — | CN | disclosed |
| US-20060147378-A1 | Azulene dimer-quenched, near-infrared fluorescent probes | THE GENERAL HOSPITAL CORPORATION | 2006-07-06 | — | — | US | disclosed |
| US-6800701-B2 | USING COORDINATION CATALYSTS | DOW GLOBAL TECHNOLOGIES INC. | 2004-10-05 | — | — | US | disclosed |
| WO-2004028449-A2 | AZULENE DIMER-QUENCHED, NEAR-INFRARED FLUORESCENT PROBES | THE GENERAL HOSPITAL CORPORATION (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-11-20 | — | — | US | disclosed |
| US-6613921-B2 | Ligand comprising at least: a cyclopentadienyl ring, a 6,7,or 8 membered ring other than a 6-carbon aromatic ring, and an aromatic ring; said 6, 7, or 8 membered ring, is fused to both the cyclopentadienyl and the aromatic ring | DOW GLOBAL TECHNOLOGIES INC. | 2003-09-02 | — | — | US | disclosed |
| EP-1299405-A1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-05-23 | — | — | US | disclosed |
| WO-2002002577-A1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGY INC. (US) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | HTR7 1507/4885S1PR4 3751/4885TSHR 4711/4885 |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | HTR7 1507/4885S1PR4 3751/4885TSHR 4711/4885 |
| US-20060147378-A1 | Azulene dimer-quenched, near-infrared fluorescent probes | ADAM17, DNPEP, APEH | HTR7 3533/4885S1PR4 4484/4885TSHR 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.