Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949928 | 1.00 | TSHR (0.60) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL29408803 | 0.89 | GAA (0.67) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL2779101 | 0.89 | GAA (0.67) | TSHRHSD17B10HPGDGAACA1 | |
| Hydrochloric Acid SCHEMBL10938578 | 0.86 | GAA (0.63) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL17000444 | 0.86 | HSD17B10 (0.55) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL26097641 | 0.83 | HSD17B10 (0.60) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL18382554 | 0.83 | GAA (0.67) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL69259 | 0.78 | HSD17B10 (0.80) | TSHRHSD17B10HPGDCA1CA2 | |
| SCHEMBL398461 | 0.78 | GAA (0.79) | TSHRHSD17B10HPGDGAACA1 | |
| SCHEMBL5492502 | 0.78 | GAA (0.79) | TSHRHSD17B10HPGDGAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033023-A | A kind of synthetic method of the hydroxyl phenylhydrazine of 2,4 dichloro 5 | 重庆锦杉科技有限公司 | 2017-08-11 | — | — | CN | claimed |
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| CN-105916482-A | Gradual hair color compositions and methods of use thereof | 酷姆国际公司 | 2016-08-31 | — | — | CN | claimed |
| WO-2015112789-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2015-07-30 | — | — | WO | claimed |
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | claimed |
| US-8586020-B2 | Poly(organophosphazene) composition for biomaterials | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-11-19 | — | — | US | claimed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | claimed |
| EP-2540764-A2 | Poly(organophosphazene) composition for biomaterials | Korea Institute of Science and Technology (KR) | 2013-01-02 | — | — | EP | claimed |
| US-8313771-B2 | Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-11-20 | — | — | US | claimed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | claimed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | claimed |
| WO-1997011674-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1997-04-03 | — | — | WO | claimed |
| EP-0728465-B1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| EP-0728465-A1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| US-5540738-A | SIMULTANEOUSLY APPLYING IODIDE IONS, AN OXIDANT AND AN EFFECTIVE CONCENTRATION OF AN OXIDATION DYE TO PRODUCE INTENSE COLORS IN ALKALINE SOLUTION | CHAN ALEXANDER C (US) | 1996-07-30 | — | — | US | claimed |
| EP-0545257-B1 | Oxidative hair coloring compositions and process for dyeing human keratinous fibers | BRISTOL MYERS SQUIBB CO (US) | 1996-05-29 | — | — | EP | claimed |
| EP-0545257-A2 | Oxidative hair coloring compositions and process for dyeing human keratinous fibers | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| US-4904275-A | OXIDIZER | L'OREAL (FR) | 1990-02-27 | — | — | US | claimed |
| US-4394521-A | Process for the production of the Schiff's bases of 2,6-dichloro-5-hydroxy-aniline | LONZA-WERKE G.M.B.H. (DE) | 1983-07-19 | — | — | US | claimed |
| US-4129414-A | Oxidation hair colorants containing water-soluble polyhalogen 3-aminophenols as couplers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1978-12-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | TSHR 4580/4885HSD17B10 2576/4885HPGD 697/4885 |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | TSHR 929/4885HSD17B10 3355/4885HPGD 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.