SCHEMBL398482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8506796	0.82	SLC6A3 (0.42)	LMNAGAACFTRTSHRPDK2
	SCHEMBL400732	0.81	TAS2R14 (0.47)	LMNAGAAP2RX7ALDH1A1KDM4E
	SCHEMBL45490	0.79	LMNA (0.59)	LMNAGAACFTRTSHRPDK2
	SCHEMBL1508457	0.78	LMNA (0.50)	LMNAGAACFTRTSHRPDK2
	SCHEMBL726068	0.78	TAS2R14 (0.54)	LMNAGAACFTRTSHRPDK2
	SCHEMBL5239843	0.78	CTSS (0.51)	LMNAGAACFTRTSHRPDK2
	SCHEMBL2949430	0.78	LMNA (0.59)	LMNAGAACFTRTSHRPDK2
	SCHEMBL6332331	0.78	ALDH1A1 (0.48)	LMNAGAACFTRTSHRALDH1A1
	SCHEMBL22996549	0.76	ALDH1A1 (0.61)	LMNAGAACFTRTSHRALDH1A1
	SCHEMBL16961195	0.76	ALDH1A1 (0.47)	LMNAGAACFTRTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.