Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | GAA | P10253 | 3/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225674 | 0.94 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL1224858 | 0.91 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL1224417 | 0.87 | ALDH1A1 (0.77) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL1225210 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL6349339 | 0.74 | GAA (0.73) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL7058846 | 0.73 | TSHR (0.72) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL7173488 | 0.73 | ALDH1A1 (0.66) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL6081481 | 0.73 | GHSR (0.76) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL316185 | 0.73 | ALDH1A1 (0.76) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL1225498 | 0.71 | PTGS2 (0.67) | ALDH1A1MAPTGAAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064422-A2 | HEPATOCYTE GROWTH FACTOR PATHWAY ACTIVATORS IN FIBROTIC CONNECTIVE TISSUE DISEASES | ANGION BIOMEDICA CORP. (US) | 2009-05-22 | — | — | WO | disclosed |