Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080755 | 0.82 | GHSR (0.65) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL1224858 | 0.80 | ALDH1A1 (1.00) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL3636891 | 0.80 | GHSR (0.75) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL316185 | 0.79 | ALDH1A1 (0.76) | PTGS2ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL18046665 | 0.78 | PTGS2 (0.61) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL18046667 | 0.78 | PTGS2 (0.61) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL29608448 | 0.78 | PTGS2 (0.61) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL12204566 | 0.78 | TSHR (0.89) | GHSRPTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL7058846 | 0.77 | TSHR (0.72) | GHSRPTGS2ALDH1A1MAPTGAA | |
| SCHEMBL3631940 | 0.77 | GHSR (1.00) | GHSRPTGS2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | GPR119, GIPR, GLP1R | GHSR 5/4885PTGS2 2925/4885ALDH1A1 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.