SCHEMBL398499

SCHEMBL398499

C=Cc1ccccc1-c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
TP53 P04637 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022113 0.92 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL10022112 0.85 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4147124 0.82 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5632912 0.81 GRM5 (0.45) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1256789 0.80 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL893835 0.80 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30062580 0.80 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8037221 0.80 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29823771 0.80 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5414951 0.79 ADRA1A (0.40) KDM4EPOLBALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330532-B Novel phosphorescent iridium complex and preparation method and application thereof 南京邮电大学 2021-11-16 CN claimed
EP-2229414-B1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GEN ELECTRIC (US) 2012-08-15 EP claimed
EP-2229413-B1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GEN ELECTRIC (US) 2012-07-11 EP claimed
US-8110641-B2 Anionic polymerization method for styrene derivative containing pyridine as functional group GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-02-07 US claimed
US-20090203861-A1 ANIONIC POLYMERIZATION METHOD FOR STYRENE DERIVATIVE CONTAINING PYRIDINE AS FUNCTIONAL GROUP GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-08-13 US claimed
US-20240023427-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
US-20230192719-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-06-22 US disclosed
CN-110875435-B Coating type organic electroluminescent device, display device and lighting device including the same 乐金显示有限公司 2022-05-27 CN disclosed
CN-110330532-B Novel phosphorescent iridium complex and preparation method and application thereof 南京邮电大学 2021-11-16 CN disclosed
CN-110875435-A Coating type organic electroluminescent device, display device and lighting device including the same 乐金显示有限公司 2020-03-10 CN disclosed
EP-3262128-A1 CURABLE SILOXANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2018-01-03 EP disclosed
US-20170077423-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-03-16 US disclosed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 US disclosed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US disclosed
EP-0427639-B1 Use of protected amino acids in feed for sheep RHONE POULENC NUTRITION ANIMAL (FR) 1994-08-17 EP disclosed
EP-0423000-B1 Use of milk from animals, supplemented with amino acids, in cheese-making RHONE POULENC NUTRITION ANIMAL (FR) 1994-01-12 EP disclosed
EP-0427639-A1 Use of protected amino acids in feed for sheep RHONE-POULENC NUTRITION ANIMALE (FR) 1991-05-15 EP disclosed
EP-0423000-A1 Use of milk from animals, supplemented with amino acids, in cheese-making RHONE-POULENC NUTRITION ANIMALE (FR) 1991-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192719-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT OR10J3, CRY1, RPS19 KDM4E 2813/4885LMNA 3557/4885CCR1 219/4885
US-20240023427-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CCNL2, AHR, ARNT KDM4E 2868/4885LMNA 1926/4885CCR1 145/4885
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 KDM4E 1455/4885LMNA 4034/4885CCR1 3194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.