Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067966 | 0.72 | KMT2A (0.37) | KMT2A | |
| SCHEMBL7025925 | 0.67 | — | — | |
| SCHEMBL6506166 | 0.67 | KDM4E (0.45) | ALDH1A1KDM4EHSD17B10CYP2C19LMNA | |
| SCHEMBL6087635 | 0.66 | CTH (0.49) | ALDH1A1KDM4EHSD17B10CYP2C19CYP1A2 | |
| SCHEMBL2549787 | 0.66 | CTH (0.49) | ALDH1A1KDM4EHSD17B10CYP2C19CYP1A2 | |
| SCHEMBL28115995 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL28402567 | 0.65 | LMNA (0.42) | ALDH1A1KDM4EHSD17B10CYP2C19LMNA | |
| SCHEMBL8977676 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL14393314 | 0.64 | PPM1B (0.43) | ALDH1A1KDM4EHSD17B10LMNAMAPT | |
| SCHEMBL9083280 | 0.64 | PPM1B (0.43) | ALDH1A1KDM4EHSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067233-A1 | BETA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |