Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173304 | 0.85 | MEN1 (0.46) | SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3991990 | 0.84 | ACHE (0.41) | CHRM1CHRM3CHRM5MEN1KMT2A | |
| SCHEMBL3984341 | 0.82 | OPRM1 (0.43) | SMPD1 | |
| SCHEMBL3987042 | 0.78 | USP2 (0.46) | ALDH1A1MEN1KMT2AP2RX4ACHE | |
| SCHEMBL3173074 | 0.74 | HTR3E (0.41) | CHRM1CHRM3CHRM5MEN1KMT2A | |
| SCHEMBL3175166 | 0.74 | HTR3E (0.41) | CHRM1CHRM3CHRM5MEN1KMT2A | |
| SCHEMBL3987395 | 0.73 | OPRM1 (0.42) | — | |
| SCHEMBL3987430 | 0.72 | OPRK1 (0.42) | CHRM1P2RX4 | |
| SCHEMBL3991588 | 0.72 | OPRM1 (0.44) | — | |
| SCHEMBL3987816 | 0.72 | P2RX4 (0.41) | ALDH1A1MEN1KMT2AP2RX4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833826-B1 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | claimed |