Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987042 | 0.91 | USP2 (0.46) | OPRK1KCNH2OPRM1USP2P2RX4 | |
| SCHEMBL13394995 | 0.86 | OPRM1 (0.43) | OPRK1KCNH2OPRM1SIRT2SIRT1 | |
| SCHEMBL13395011 | 0.86 | OPRM1 (0.43) | OPRK1KCNH2OPRM1SIRT2SIRT1 | |
| SCHEMBL3174188 | 0.86 | OPRM1 (0.43) | OPRK1KCNH2OPRM1SIRT2SIRT1 | |
| SCHEMBL3986087 | 0.86 | OPRK1 (0.42) | OPRK1KCNH2OPRM1SIRT1CHRM1 | |
| SCHEMBL3994605 | 0.86 | USP2 (0.37) | USP2CHRM1P2RX4 | |
| SCHEMBL3984341 | 0.85 | OPRM1 (0.43) | OPRK1KCNH2OPRM1 | |
| SCHEMBL3987734 | 0.84 | TRPM8 (0.35) | USP2P2RX4TRPM8 | |
| SCHEMBL4111531 | 0.84 | MAOA (0.37) | OPRM1USP2P2RX4 | |
| SCHEMBL3986089 | 0.83 | OPRM1 (0.42) | OPRK1KCNH2OPRM1CHRM1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833826-B1 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | claimed |