Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 10/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 10/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 10/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 10/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 10/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 10/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 10/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 10/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 10/20 | 0.40 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 10/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.40 |
| ▸ | PSMB3 | P49720 | 10/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 10/20 | 0.40 |
| ▸ | PSMA6 | P60900 | 10/20 | 0.40 |
| ▸ | PSMA8 | Q8TAA3 | 10/20 | 0.40 |
| ▸ | PSMB7 | Q99436 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989377 | 0.85 | CA2 (0.39) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL3987635 | 0.84 | CA2 (0.38) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL3993264 | 0.76 | MAPT (0.36) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL3993261 | 0.76 | PSMB11 (0.34) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL4657183 | 0.72 | CTSL (0.47) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7788731 | 0.71 | CA4 (0.41) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL4656413 | 0.70 | SYK (0.51) | CTSDCA2CA5ACA1 | |
| SCHEMBL4656232 | 0.70 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL13979534 | 0.70 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL3989379 | 0.68 | ABCB1 (0.36) | CA2CA5ACA1CASP3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |