Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.43 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656413 | 0.89 | SYK (0.51) | CTSLCTSKSYKCTSDCA2 | |
| SCHEMBL4657191 | 0.88 | APP (0.40) | CTSLCTSKSYKPSMB1PSMB5 | |
| SCHEMBL4657113 | 0.85 | SYK (0.60) | CTSLCTSKSYKCTRB1 | |
| SCHEMBL3987635 | 0.80 | CA2 (0.38) | CTSLCTSKCTSDPSMB1PSMB5 | |
| SCHEMBL7788731 | 0.80 | CA4 (0.41) | CTSLCTSKCTSDPSMB1PSMB5 | |
| SCHEMBL13979534 | 0.79 | OPRK1 (0.42) | — | |
| SCHEMBL3989377 | 0.78 | CA2 (0.39) | CTSDPSMB1PSMB5PSMB2PSMB11 | |
| SCHEMBL4656418 | 0.78 | APP (0.43) | CTSKSYKCA2 | |
| SCHEMBL3989460 | 0.75 | CTSL (0.45) | CTSLCTSKSYKCTRB1 | |
| SCHEMBL3989464 | 0.75 | CTSL (0.45) | CTSLCTSKSYKCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1006122-A1 | PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-06-07 | — | — | EP | disclosed |