Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408262 | 0.94 | CHRM2 (0.46) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL5081884 | 0.92 | L3MBTL1 (0.46) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL3936513 | 0.88 | PIK3CD (0.48) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL30353573 | 0.84 | TSHR (0.41) | CYP1A2PIK3CDKMT2ATSHRPOLB | |
| SCHEMBL21052112 | 0.83 | CHRM2 (0.47) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL261644 | 0.82 | PIK3CD (0.58) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL14168930 | 0.81 | POLB (0.43) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| O-Xylene SCHEMBL28960722 | 0.79 | ADRA1B (0.50) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL163174 | 0.78 | — | — | |
| SCHEMBL6740977 | 0.78 | MAPT (0.50) | CHRM2CHRM5CHRM1CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133569-A1 | CARBON NANOTUBE SUSPENSIONS AND METHODS OF MAKING THE SAME | CHEIL INDUSTRIES, INC. (KR) | 2015-05-14 | — | — | US | claimed |
| US-20150087858-A1 | CARBON NANOTUBE SUSPENSIONS AND METHODS OF MAKING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2015-03-26 | — | — | US | claimed |
| CN-118440085-A | Method for preparing DBU and DBN by utilizing fixed bed reactor | 济宁无内新材料技术研发中心(有限合伙) | 2024-08-06 | — | — | CN | disclosed |
| US-20240246908-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2024-07-25 | — | — | US | disclosed |
| CN-111466043-B | Porous composite separator for secondary battery and lithium secondary battery comprising same | SK新技术株式会社 | 2023-05-30 | — | — | CN | disclosed |
| EP-3066065-B1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID AMIDES, DI-, TRI- OR POLYPEPTIDES OR PEPTIDE AMIDES | EVONIK DEGUSSA GMBH (DE) | 2019-06-19 | — | — | EP | disclosed |
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| CN-1215727-A | Bicyclic amidine and its use as catalyst | LONZA AG (CH) | 1999-05-05 | — | — | CN | disclosed |
| CN-1042227-C | Process for preparing bicyclic amidines | LONZA AG (CH) | 1999-02-24 | — | — | CN | disclosed |
| WO-1999006397-A2 | PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0662476-B1 | Process for the preparation of bicyclic amidines | LONZA AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| EP-0885215-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5723605-A | Bicyclic amidines, process for their preparation, and their use as catalyst | LONZA LTD. (CH) | 1998-03-03 | — | — | US | disclosed |
| WO-1997030045-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | disclosed |
| CN-1106406-A | Bicyclic amidines, method for the production and use thereof as catalysts | LONZA AG (CH) | 1995-08-09 | — | — | CN | disclosed |
| EP-0662476-A1 | Bicyclic amidines, process for their preparation and their use as catalysts | LONZA AG (CH) | 1995-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246908-A1 | TEAD INHIBITORS | TEAD3, TEAD1, TEAD2 | CHRM2 886/4885CHRM5 1230/4885CHRM1 273/4885 |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | DAO, DDC, HDGF | CHRM2 3452/4885CHRM5 3880/4885CHRM1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.