Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.40 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.40 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989682 | 0.92 | TACR1 (0.48) | ATMTACR1MEN1KMT2A | |
| SCHEMBL3987548 | 0.85 | ERCC1 (0.30) | — | |
| SCHEMBL3995160 | 0.79 | REN (0.33) | ATM | |
| SCHEMBL3989519 | 0.79 | CASP3 (0.38) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL27553310 | 0.77 | TACR1 (0.47) | ATMTACR1MEN1KMT2A | |
| SCHEMBL4656413 | 0.75 | SYK (0.51) | CA2CA5AATMCA1CTSD | |
| SCHEMBL4657183 | 0.74 | CTSL (0.47) | CA2CA5ACA1PSMB11PSMA7 | |
| SCHEMBL3989460 | 0.72 | CTSL (0.45) | TACR1 | |
| SCHEMBL3989464 | 0.72 | CTSL (0.45) | TACR1 | |
| SCHEMBL17359183 | 0.72 | ATM (0.59) | ATMTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |