Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796803 | 0.86 | SCN9A (0.36) | MMP1SCN9AGAA | |
| SCHEMBL3991380 | 0.86 | SCN9A (0.36) | MMP1SCN9AGAA | |
| SCHEMBL3989372 | 0.83 | PTPRB (0.38) | CTSKGAA | |
| SCHEMBL3994576 | 0.81 | ROCK2 (0.30) | — | |
| SCHEMBL3989537 | 0.79 | MMP1 (0.39) | MMP1 | |
| SCHEMBL3994577 | 0.79 | — | — | |
| SCHEMBL3987520 | 0.74 | CTSL (0.41) | CTSK | |
| SCHEMBL3989338 | 0.73 | MMP1 (0.41) | MMP1GAA | |
| SCHEMBL4656090 | 0.72 | CTSS (0.45) | CTSKPTPN1 | |
| SCHEMBL4656092 | 0.72 | CTSS (0.45) | CTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |