Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657546 | 0.84 | ABCB1 (0.40) | CTSLCTSBCTSSALDH1A1 | |
| SCHEMBL3991380 | 0.81 | SCN9A (0.36) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL13796803 | 0.81 | SCN9A (0.36) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL3989338 | 0.80 | MMP1 (0.41) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL3989633 | 0.79 | CTSK (0.37) | MMP1 | |
| SCHEMBL3989379 | 0.79 | ABCB1 (0.36) | CTSLCTSBCTSSALDH1A1 | |
| SCHEMBL3989609 | 0.75 | CTSK (0.34) | CTSLCTSBCTSSALDH1A1 | |
| SCHEMBL3988488 | 0.73 | POLB (0.43) | MMP1ANPEPMMP3MMP9ALDH1A1 | |
| SCHEMBL4656092 | 0.70 | CTSS (0.45) | CTSLCTSBCTSS | |
| SCHEMBL3987520 | 0.69 | CTSL (0.41) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |