⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991102 | 0.72 | — | — | |
| SCHEMBL16475117 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL24262371 | 0.69 | SLC22A12 (0.40) | — | |
| SCHEMBL19278216 | 0.69 | ABL1 (0.36) | — | |
| SCHEMBL14321691 | 0.69 | BCHE (0.33) | — | |
| SCHEMBL5511626 | 0.66 | GRM2 (0.32) | — | |
| SCHEMBL30776600 | 0.66 | GRM2 (0.32) | — | |
| SCHEMBL2369513 | 0.66 | PARP1 (0.36) | — | |
| SCHEMBL23292002 | 0.65 | DGAT1 (0.40) | — | |
| SCHEMBL3218543 | 0.65 | ENPP3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589206-B2 | Pyrrolopyridine derivatives | GLAXO GROUP LIMITED (GB) | 2009-09-15 | — | — | US | disclosed |
| US-7589206-B2 | Pyrrolopyridine derivatives | GLAXO GROUP LIMITED (GB) | 2009-09-15 | — | — | US | disclosed |
| EP-1753764-B1 | PYRROLOPYRIDINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2008-10-29 | — | — | EP | disclosed |
| US-20070219229-A1 | Pyrrolopyridine Derivatives | GLAXO GROUP LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |
| US-20070219229-A1 | Pyrrolopyridine Derivatives | GLAXO GROUP LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |
| CN-101001859-A | Pyrrolopyridine derivatives | GLAXO GROUP LTD (GB) | 2007-07-18 | — | — | CN | disclosed |
| EP-1753764-A1 | PYRROLOPYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005121140-A1 | PYRROLOPYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |