Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675108 | 0.80 | ENPP2 (0.52) | ENPP2CXCR2LMNAHTTGAA | |
| SCHEMBL4274920 | 0.80 | LMNA (0.55) | LMNAHTTGAAALDH1A1PKM | |
| SCHEMBL4057693 | 0.75 | NNMT (0.47) | LMNAALDH1A1MEN1PABPC1KMT2A | |
| SCHEMBL9374502 | 0.73 | KDR (0.50) | CXCR2PKM | |
| SCHEMBL3002786 | 0.72 | LMNA (0.49) | LMNAHTTGAAALDH1A1PKM | |
| SCHEMBL26697665 | 0.72 | MEN1 (0.59) | SGMS2GCKMEN1KMT2A | |
| SCHEMBL10628510 | 0.72 | SGMS2 (0.48) | HTTGAASGMS2GCKMEN1 | |
| SCHEMBL28747791 | 0.71 | PKM (0.46) | ENPP2LMNAHTTGAAALDH1A1 | |
| SCHEMBL25343798 | 0.70 | ALDH1A1 (0.50) | LMNAHTTGAAALDH1A1MEN1 | |
| SCHEMBL518381 | 0.70 | ALDH1A1 (0.50) | LMNAHTTGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |